KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAMTS6
All Species:
15.76
Human Site:
S230
Identified Species:
34.67
UniProt:
Q9UKP5
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UKP5
NP_922932.2
1117
125273
S230
D
T
S
T
V
S
Y
S
L
P
I
N
N
T
H
Chimpanzee
Pan troglodytes
XP_526907
1117
125238
S230
D
T
S
T
V
S
Y
S
L
P
I
N
N
T
H
Rhesus Macaque
Macaca mulatta
XP_001084793
1117
125301
S230
D
T
S
T
F
S
Y
S
L
P
I
N
N
T
H
Dog
Lupus familis
XP_535255
1117
125043
S230
E
T
S
A
F
P
S
S
L
P
I
N
G
S
H
Cat
Felis silvestris
Mouse
Mus musculus
P58459
1104
121067
Q228
G
N
E
S
E
R
G
Q
L
G
L
K
R
S
V
Rat
Rattus norvegicus
Q1EHB3
1595
175796
C299
D
D
T
L
K
N
F
C
R
W
Q
K
N
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513889
903
100601
Q43
L
S
Y
L
E
H
Y
Q
L
T
I
P
I
R
V
Chicken
Gallus gallus
XP_424749
1118
125075
S230
D
G
S
A
F
P
T
S
L
P
V
N
D
T
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001923204
1116
124633
V229
K
L
N
P
D
F
P
V
L
G
V
D
S
L
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19791
2150
242563
S246
F
D
H
L
N
S
T
S
V
N
E
T
E
T
T
Sea Urchin
Strong. purpuratus
XP_001180742
1320
148448
Q348
H
D
V
E
K
K
L
Q
D
P
E
Y
L
A
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.6
98.4
N.A.
59.7
30.4
N.A.
72.9
92.4
N.A.
82.8
N.A.
N.A.
N.A.
21.4
39.7
Protein Similarity:
100
99.9
99.7
98.9
N.A.
74.4
41.5
N.A.
75.7
95.8
N.A.
90.1
N.A.
N.A.
N.A.
31.1
54.6
P-Site Identity:
100
100
93.3
53.3
N.A.
6.6
13.3
N.A.
20
46.6
N.A.
6.6
N.A.
N.A.
N.A.
20
13.3
P-Site Similarity:
100
100
93.3
66.6
N.A.
26.6
40
N.A.
26.6
60
N.A.
33.3
N.A.
N.A.
N.A.
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
19
0
0
0
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
46
28
0
0
10
0
0
0
10
0
0
10
10
0
0
% D
% Glu:
10
0
10
10
19
0
0
0
0
0
19
0
10
0
0
% E
% Phe:
10
0
0
0
28
10
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
0
0
0
0
10
0
0
19
0
0
10
0
0
% G
% His:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
46
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
46
0
10
0
0
% I
% Lys:
10
0
0
0
19
10
0
0
0
0
0
19
0
0
0
% K
% Leu:
10
10
0
28
0
0
10
0
73
0
10
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
10
0
10
10
0
0
0
10
0
46
37
0
10
% N
% Pro:
0
0
0
10
0
19
10
0
0
55
0
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
28
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
0
10
0
0
0
10
10
0
% R
% Ser:
0
10
46
10
0
37
10
55
0
0
0
0
10
19
0
% S
% Thr:
0
37
10
28
0
0
19
0
0
10
0
10
0
46
10
% T
% Val:
0
0
10
0
19
0
0
10
10
0
19
0
0
10
19
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
37
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _